GI Cancer

NRG GI008

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

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URCC 19185

Multicenter Randomized Controlled Trial comparing Brief Behavioral Therapy for Cancer Related Insomnia (BBT-CI) and Healthy Eating Education Learning (HEAL)

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EAY191-A3 ***Cohort 3 (Pancreatic Cancer) and Cohort 4 (Other RAS-Mutant Tumors) Temporarily Suspended***

Palbociclib and Binimetinib in RAS-Mutant Cancers: A ComboMATCH Treatment Trial

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ALLIANCE EAY191-A6

FOLFOX in Combination with Binimetinib as 2nd Line Therapy for Patients with Advanced Biliary Tract Cancers with MAPK Pathway Alterations: A ComboMATCH Treatment Trial

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URCC 22063

Longitudinal Observational Trial to Uncover Subtypes of Cancer Cachexia (LOTUS-CC)

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AFT-63 ***Cohort C (Non-Lung Cancer) Permanently Closed***

DNA Evaluation of Fragments for Early Interception – Lung Cancer Training Study (DELFI-L101 Study)

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EAY191 (ComboMATCH) **If biopsy needed, TBD at MBMC**

Molecular Analysis for Combination Therapy Choice

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ALLIANCE A212102 **AT MBMC ONLY** **As of 8/1/23 the following Healthy Control Cohorts are Open (all others are Closed as of 2/22/23): Non-White Male Participants Age 60 or More Without Cancer Diagnosis and Non-White Male Participants Under Age 60 Without Cancer Diagnosis** **Effective with the release of Update #02, enrollment to the thyroid, melanoma, and sarcoma cancer cohorts has been closed.**

Blinded Reference Set For Multicancer Early Detection Blood Tests

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URCC 19075 **MBMC ONLY**

Multi-Center Randomized Controlled Phase II Trial of Exercise to Treat Chemotherapy-Induced Peripheral Neuropathy (CIPN)

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ECOG-ACRIN EA2197 (JIT – IF A POSSIBLE PATIENT IS IDENTIFIED, NOTIFY CRA ASAP AS IT WILL TAKE TIME TO OPEN TRIAL THROUGH NCORP)

OPTIMAL PERIOPERATIVE THERAPY FOR INCIDENTAL GALLBLADDER CANCER (OPT-IN): A RANDOMIZED PHASE II/III TRIAL

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